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AACR 2012 /
Galeterone safe and effective against prostate cancer

31st Mar - 4th Apr 2012

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Published: 13.04.12
Views: 3468
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Dr Bruce Montgomery - University of Washington, Seattle, USA

Castration-resistant prostate cancer (CRPC) is an advanced form of prostate cancer that occurs when the disease progresses after treatment with androgen deprivation therapy. Galeterone works against CRPC by blocking the androgen receptor, reducing levels of the ligand that binds to the receptor and degrading the androgen receptor protein.

 

Patients with castration-resistant prostate cancer had limited side effects and in many cases a drop in prostate-specific antigen expression with galeterone (TOK-001), a small-molecule oral drug, according to phase I data presented at the AACR Annual Meeting 2012.

 

ecancerNews Coverage: Early clinical data show galeterone safe, effective against prostate cancer

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Founding partners

European Cancer Organisation European Institute of Oncology

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Foundazione Umberto Veronesi Fondazione IEO Swiss Bridge

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ecancer Global Foundation