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ASCO 2019 /
Biomarker analysis from JAVELIN Renal 101: Avelumab plus axitinib versus sunitinib in aRCC

31st May - 4th Jun 2019

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Published: 01.06.19
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Dr Toni Choueiri - Dana-Farber Cancer Institute, Boston, USA

Dr Toni Choueiri talks to ecancer at the 2019 American Society of Clinical Oncology (ASCO) Annual Meeting about the biomarker analysis from the JAVELIN Renal 101 trial which observed avelumab plus axitinib versus sunitinib in advanced renal cell carcinoma (aRCC).

He reports that PD-L1 as a biomarker was a negative prognostic indicator in patients who received sunitinib and didn't impact the benefit from avelumab plus axitinib.

Dr Choueiri explains however that high CD8 was associated with high progression free survival in the combination arm and the opposite in patients who received sunitinib.

ecancer's filming has been kindly supported by Amgen through the ecancer Global Foundation. ecancer is editorially independent and there is no influence over content.
 

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Founding partners

European Cancer Organisation European Institute of Oncology

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