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Treatment options for elderly CLL patients

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Published: 29.03.11
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Prof Peter Hillmen - St James's University Hospital, Leeds, UK

Prof Peter Hillmen speaks about the treatment options available for elderly chronic lymphocytic leukaemia (CLL). The current standard of care is chlorambucil but patients can achieve a deeper remission if treated with FCR (fludarabine, cyclophosphamide and rituximab). Patients may only receive FCR if they have reasonably good renal function and the FCR drug combination is highly immunosuppressive, making it unsuitable for patients with a high risk of infections.
Prof Hillmen discusses how clinicians should decide on the best treatment for each individual, outlines the need for large randomised trials of new drugs such as bendamustine and talks about the prospect of targeted therapies.

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