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POUT: Phase III randomised trial of perioperative chemotherapy vs surveillance in upper tract urothelial cancer

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Published: 08.02.18
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Dr Alison Birtle - Lancashire Teaching Hospitals NHS Foundation Trust, Lancashire, UK

Dr Birtle speaks with ecancer at the 2018 ASCO Genitourinary Cancers Symposium about the results of the POUT study that addresses whether adjuvant chemotherapy improves disease free survival for patients with histologically confirmed pT2-T4 N0-3 M0 upper tract urothelial cancer.

She goes on to state that at the time of interim analysis, median follow-up was 17.6 months and grade ≥3 toxicities were reported in 60% chemotherapy patients and 24% surveillance patients.

Dr Birtle then goes on to discuss the results of the study, highlighting that adjuvant chemotherapy improved disease free survival and progression free survival in the upper tract urothelial cancer patient cohort.

 

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