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Respiratory microbiomes and lung cancer from mining communities

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Published: 21.09.17
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Prof Luis Mur - Aberystwyth University, Aberystywth, Wales

Prof Luis Mur talks to ecancer at the Microbiome in Cancer and Beyond 2017 meeting about lung cancer and chronic obstructive pulmonary disease (COPD) which is particularly relevant to the mining districts of Wales. This is vital since early detection rates are as low as 5 %.

With assistance from the NHS, various samples are being collected to understand the biology of each microbiome, their relationship with lung cancer, and potential issues such as antibiotic resistance. Highly influential metabolites are identified and further studied with relation to the microbiome; these include short fatty acids, amides and sugars.

Dr Mur also describes the variation in between the upper and lower respiratory tracts, and how their relationships with lung cancer and COPD.

Dr Mur specialises in deriving drugs from natural sources, mainly due to some adverse effects and resistance arising from synthetic drugs. This future of this research looks very promising. 

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