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Durvalumab in novel combinations for head and neck cancer

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Published: 11.09.17
Views: 768

Dr Ezra Cohen - UC San Diego Health, San Diego, USA

Dr Cohen speaks with ecancer at the ESMO 2017 Congress in Madrid about the SCORES study assessing safety, tolerability, and preliminary anti-tumour activity of durvalumab plus AZD9150 or AZD5069 in patients with advanced solid malignancies and squamous cell carcinoma of the head and neck. 

He discusses how, of the two molecules targeting CXCR2 and STAT3 pathways, the influence of STAT3 on myeloid cells in the tumour microenvironment leads to significant response with a manageable toxicity profile.

Dr Cohen also spoke with ecancer about the KEYNOTE 40 trial of pembrolizumab in relapsed HNSCC, here.

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