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The METRIC trial of trametinib, five years on

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Published: 10.09.17
Views: 244

Prof Dirk Schadendorf - Essen University Hospital, Essen, Germany

Prof Schadendorf speaks with ecancer at ESMO 2017 about the METRIC trial in melanoma, which initially showed a survival benefit for trametinib.

He reports that, with 5 years of safety and survival data now available, the initial benefits have not translated to a long term survival benefit.

Prof Schadendorf discusses how a changing landscape of targeted and combination therapies has now opened treatment options and dramatically extended patients life expectancy, so while trametinib monotherapy may not retain its initial benefits, it has been an essential stepping stone to the latest generation of melanoma treatments.

ecancer's filming has been kindly supported by Amgen through the ECMS Foundation. ecancer is editorially independent and there is no influence over content.

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