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Phase Ib/II trial of combination PD-1 therapy against kidney cancer

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Published: 09.09.17
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Dr Chung-Han Lee - Memorial Sloan Kettering Cancer Center, New York, USA

Dr Lee speaks with ecancer at ESMO 2017 about the early results of combining lenvatinib, one of the current treatment options against metastatic renal carcinoma, with anti-PD1 pembrolizumab.

He outlines the endpoints for the trial including overall response (OR) at 24 weeks, and notes the improved response for treatment naïve patients compared to those who had been previously treated.

While median PFS has not yet been met, Dr Lee is optimistic that the responses so far will translate to survival, and introduces phase III trials including lenvatinib and pembrolizumab as an investigative arm.

Fore more on this study, read our news coverage here.

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