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Neratinib in HER2 or HER3 mutant solid tumours

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Published: 10.04.17
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Dr David Hyman - Memorial Sloan Kettering Cancer Center, New York, USA

Dr Hyman speaks with ecancer at AACR 2017 to discuss results of the phase II SUMMIT trial of neratinib, which you can read more about here, or watch the press conference in which these results were presented.

He describes the response of patients with HER2 mutations to neratinib, most notably in breast, cervical and biliary cancers, and considers the influence of tumour type and specific mutation to explain the lack of responses in patients with HER3 mutations and HER2 colorectal tumours.

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