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https://doi.org/10.3332/ecancer.2015.525

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Curcumin modulates cellular AP-1, NF-kB, and HPV16 E6 proteins in oral cancer

22 Apr 2015

Alok Mishra, Rakesh Kumar, Abhishek Tyagi, Indu Kohaar, Suresh Hedau, Alok C Bharti, Subhodeep Sarker, Dipankar Dey, Daman Saluja, Bhudev Das

In this study, we investigated the effects of the natural antioxidant curcumin on the HPV16-positive oral carcinoma cell line 93VU147T and demonstrated that curcumin is not only a potent inhibitor for the activity of host nuclear transcription factors AP-1 and NF-kB but it also selectively suppresses transcription of the HPV16/E6 oncogene during the carcinogenic process in oral cancer cells. This study suggests a therapeutic potential of curcumin for high-risk human papilloma virus (HPV)-infected oral cancers.

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2007-long-term-outcomes-with-non-dose-dense-chemotherapy-for-ewing-sarcoma-a-follow-up-of-the-cohort-treated-with-eft-2001-protocol

Research: Long-term outcomes with non-dose dense chemotherapy for Ewing sarcoma – a follow up of the cohort treated with EFT-2001 protocol

Badira Cheriyalinkal Parambil, Girish Chinnaswamy, Maya Prasad, Venkata Rama Mohan Gollamudi, Ajay Puri, Ashish Gulia, Sajid Qureshi, Prakash Nayak, Manish Pruthi, Siddhartha Laskar, Nehal Khanna, Jifmi Jose Manjali, Amit Janu, Sneha Shah, Nilendu Purandare, Mukta Ramadwar, Poonam Panjwani, Bharat Rekhi, Pallavi Rane, Shripad Banavali

7 Oct 2025

https://doi.org/10.3332/ecancer.2025.2007

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