ecancermedicalscience

Submit article

https://doi.org/10.3332/ecancer.2015.525

Abstract | Full Article |

Research

Curcumin modulates cellular AP-1, NF-kB, and HPV16 E6 proteins in oral cancer

22 Apr 2015

Alok Mishra, Rakesh Kumar, Abhishek Tyagi, Indu Kohaar, Suresh Hedau, Alok C Bharti, Subhodeep Sarker, Dipankar Dey, Daman Saluja, Bhudev Das

In this study, we investigated the effects of the natural antioxidant curcumin on the HPV16-positive oral carcinoma cell line 93VU147T and demonstrated that curcumin is not only a potent inhibitor for the activity of host nuclear transcription factors AP-1 and NF-kB but it also selectively suppresses transcription of the HPV16/E6 oncogene during the carcinogenic process in oral cancer cells. This study suggests a therapeutic potential of curcumin for high-risk human papilloma virus (HPV)-infected oral cancers.

Article metrics: 7651 views

3673

3978

2170-efficacy-of-pembrolizumab-and-oncolytic-viral-therapy-in-stage-iii-esophageal-cancer-a-narrative-review

Review: Efficacy of pembrolizumab and oncolytic viral therapy in stage III esophageal cancer: a narrative review

Rajsinh Bhosale, Lamiya Pirzada, Safiyyah Khan, Aqsa Zainab, Shravya Subashini Sivaramakrishnan, Areeba Mariam Mehmood, Pawan Sapkota Upadhya

21 Jul 2026

https://doi.org/10.3332/ecancer.2026.2170

Abstract | Full Article | PDF

2171-use-of-18f-alf-nota-octreotide-pet-ct-as-a-diagnostic-test-for-the-detection-of-neuroendocrine-tumours-a-histopathology-referenced-diagnostic-accuracy-study

Clinical Study: Use of [18F]AlF-NOTA-Octreotide PET/CT as a diagnostic test for the detection of neuroendocrine tumours: a histopathology-referenced diagnostic accuracy study

Paulina B Crespo-Morfin, Rodrigo Figueroa-Mendez, Eleazar Ignacio-Álvarez, Miguel A Ávila-Rodríguez, Alfredo A Reza-Albarrán

21 Jul 2026

https://doi.org/10.3332/ecancer.2026.2171

Abstract | Full Article | PDF

2172-impact-of-trastuzumab-on-anti-mullerian-amh-levels-in-patients-undergoing-neo-adjuvant-treatment-for-breast-cancer-a-systematic-review

Review: Impact of trastuzumab on Anti-Müllerian (AMH) levels in patients undergoing (neo) adjuvant treatment for breast cancer: a systematic review

Roberta Monteiro Batista Sarmento, José Roberto Lapa e Silva, Gustavo Arantes Rosa Maciel, Claudia Ferrer, José Bines

21 Jul 2026

https://doi.org/10.3332/ecancer.2026.2172

Abstract | Full Article | PDF

2167-variation-in-reported-incidence-and-treatment-approaches-in-de-novo-oligo-metastatic-and-oligo-recurrent-non-nasopharyngeal-head-and-neck-cancers-across-the-continents-subgroup-analysis-from-a-head-and-neck-cancer-international-group-hncig-survey

Short Communication: Variation in reported incidence and treatment approaches in de-novo oligo-metastatic and oligo-recurrent non-nasopharyngeal head and neck cancers across the continents: subgroup analysis from a head and neck cancer international group (HNCIG) survey

Monali Swain, Sarbani Ghosh-Laskar, Lachlan McDowell, Christina Henson, Pierluigi Bonomo, Sadhana Kannan, Timothy Malouff, Akihiro Homma, Alexander Rühle, Anna Lee, Francesca Caparrotti, James Bates, Jorgen Johansen, Juliette Thariat, Marco Ferrari, Miguel Mayo-Yáñez, Sarah Hamilton, Sue S Yom, Hisham Mehanna, Petr Szturz

20 Jul 2026

https://doi.org/10.3332/ecancer.2026.2167

Abstract | Full Article | PDF