My ePortfolio Register   
 

Abstract | Full HTML Article | PDF ecancer 9 499 / https://doi.org/10.3332/ecancer.2015.499

Case Report

Targeted therapy with propranolol and metronomic chemotherapy combination: sustained complete response of a relapsing metastatic angiosarcoma

We report here a case of a 69-year-old woman with a relapsing metastatic angiosarcoma treated with a combination of metronomic chemotherapy and propranolol. The beta blockers were added since the tumour was positive for betaadrenergic receptor. A complete response was quickly obtained and lasted for 20 months.

With this case, the combination of metronomic chemotherapy and propranolol in angiosarcoma warrants additional studies and illustrates the potential of metronomics to generate innovative yet inexpensive targeted therapies for both high-income and low-/middle-income countries.

Keywords: angiosarcoma, metronomic chemotherapy, drug repositioning, palliative treatment, beta-blockers, propranolol, celecoxib, etoposide, cyclophosphamide

Loading Article Metrics ... Please wait

Related articles

Research: The mortality-incidence ratio as an indicator of five-year cancer survival in metropolitan Lima

Abstract | Full Article | PDF | Spanish Published: 18 Jan 2018 / https://doi.org/10.3332/ecancer.2018.799

Review: Natural history of castration-resistant prostate cancer in sub-Saharan African black men: a single-centre study of Nigerian men

Abstract | Full Article | PDF Published: 16 Jan 2018 / https://doi.org/10.3332/ecancer.2018.797

Conference Report: Highlights from the Inaugural International Cancer Microbiome Consortium Meeting (ICMC), 5–6 September 2017, London, UK

Abstract | Full Article | PDF Published: 20 Dec 2017 / https://doi.org/10.3332/ecancer.2017.791

Conference Report: United against cancer: prevention to end-of-life care—highlights from the Uganda Cancer Institute–Palliative Care Association of Uganda Joint International Conference on Cancer and Palliative Care and the 7th Palliative Care Conference, 24–25 August 2017, Kampala, Uganda

Abstract | Full Article | PDF Published: 14 Dec 2017 / https://doi.org/10.3332/ecancer.2017.790

Case Report: Primary non-Hodgkin lymphoma of the prostate: a case report

Abstract | Full Article | PDF Published: 12 Dec 2017 / https://doi.org/10.3332/ecancer.2017.789



Founding partners

European Cancer Organisation European Institute of Oncology

Founding Charities

Foundazione Umberto Veronesi Fondazione IEO Swiss Bridge

Published by

Cancer Intelligence