ecancermedicalscience

Case Report

Targeted therapy with propranolol and metronomic chemotherapy combination: sustained complete response of a relapsing metastatic angiosarcoma

8 Jan 2015
Shripad Banavali, Eddy Pasquier, Nicolas André

We report here a case of a 69-year-old woman with a relapsing metastatic angiosarcoma treated with a combination of metronomic chemotherapy and propranolol. The beta blockers were added since the tumour was positive for betaadrenergic receptor. A complete response was quickly obtained and lasted for 20 months.

With this case, the combination of metronomic chemotherapy and propranolol in angiosarcoma warrants additional studies and illustrates the potential of metronomics to generate innovative yet inexpensive targeted therapies for both high-income and low-/middle-income countries.

Related Articles

Camilla Engelsmann, Gitte Wooler, Vladimira Horvat, Shailesh Balasaheb Kolekar
Simran Malik, Sudipta Mukherjee, Pralay Shankar Ghosh, Santanu Bagchi, Gaurav Goel, Soumyadip Chatterji, Saugata Sen, Debashree Guha Adhya, Sangeeta Das Bhattacharya, Sanjay Bhattacharya
Sasongko Hadi Priyono, Winardi Budiwinata, Budianto Tedjowitono, Effendy, Muhamad Daffa Ibnurasy Pratama
Rohini Sebastian, Josh Thomas Georgy, Arun George, Prisca Santhanam, Raiza Philip, Anjana Joel, Ajoy Oommen John, Deepa Susan Joy Philip, Divya Bala Thumaty, Thomas Alex Kodiatte, Ashish Singh, Rekha Pai
Sidhart Misra, Zainab Yusufali Motiwala, Ayyaz Mulla, Jagatheswaran Chinnathambi, Danny Darlington Carbin
Faiza Ahmed, Aqsa Amjad, Eman Anwar, Mohammad Saad Saleem Naviwala, Warda Saleem, Nawazish Zehra, Munira Moosajee, Yasmin Abdul Rashid