ecancermedicalscience

Case Report

Targeted therapy with propranolol and metronomic chemotherapy combination: sustained complete response of a relapsing metastatic angiosarcoma

8 Jan 2015
Shripad Banavali, Eddy Pasquier, Nicolas André

We report here a case of a 69-year-old woman with a relapsing metastatic angiosarcoma treated with a combination of metronomic chemotherapy and propranolol. The beta blockers were added since the tumour was positive for betaadrenergic receptor. A complete response was quickly obtained and lasted for 20 months.

With this case, the combination of metronomic chemotherapy and propranolol in angiosarcoma warrants additional studies and illustrates the potential of metronomics to generate innovative yet inexpensive targeted therapies for both high-income and low-/middle-income countries.

Related Articles

Matías A Atencio, Elías J Ortega Chahla, Mirko Vidic, Candela V Giuffré, Mickaela Echavarría Demichelis, Joaquín A Luini, Franco E Espinoza, Ana M Rosas, María Cruz Germain, Abril Montani, Iñaki M Dopazo Danieli, Joel A Schernenco, Lucas G Durán, María E Esandi
Ravikant Singh, Atul Budukh Suvarna Kolekar, Gaurav Kumar, Burhanuddin Qayyumi, Tulika Gupta, Zikki Hassan Fatima, Narpat Padvi, Samyukta Shivashankar, Alisha Shah, Deepak Gupta, Nishant Kumar, Kumar Prabhash
Ashutosh Mishra, Amit Kumar, Ajay Gogia, Chinmay Bagla, Gajendra Pandit, Jyoti Sharma, Jyoutishman Saikia, Rohan Kapoor, D N Sharma, Atul Batra, Surendra Saini, Supriya Mallick, Nishkarsh Gupta, Brajesh Ratre, Ruchi Rathore, Sandeep Mathur, Sunil Kumar, Suryanarayana Deo