ecancermedicalscience

Case Report

Neuroendocrine carcinoma of the cervix presenting as intractable hyponatremic seizures due to paraneoplastic SIADH—a rare case report and brief review of the literature

31 Jul 2014
Santhosh Kuriakose, N Umadevi, Sheela Mathew, NK Supriya, KP Aravindan, DS Smitha, G Amritha Malini

Herein is presented an interesting case of small-cell neuroendocrine carcinoma of the cervix which initially manifests as seizures due to hyponatremia caused by paraneoplastic syndrome of inappropriate anti diuretic hormone (SIADH). Awareness of a paraneoplastic syndrome at presentation can lead to early diagnosis and early initiation of treatment. The management is also unique in that it combines treating the paraneoplastic aspects as well as targeting the tumour itself. Multimodality treatment gives the best outcome in this aggressive tumour.

Related Articles

Brindha Senthil Kumar, Ponnagoundanpudur Sundaramoorthy Kirit, Nachimuthu Senthil Kumar, Shanmuganandam Sumathi, Samuel Lalhruaizela, Lal Hruaitluanga, Lal Hmingliana
Daniel F Pilco-Janeta, Myriam De la Cruz-Puebla, Daisy Guamán-Pilco, Diego Montenegro, Philipp Novotny, William Miranda
Parth Sharma, Mongjam Meghachandra Singh, Amod Laxmikant Borle, Disha Agrawal, Anurita Srivastava, Ravi Meher
Samvel Bardakhchyan, Sona Karamyan, Hovsep Gharadaghyan, Davit Zohrabyan, Liana Safaryan, Armen Avagyan, Lilit Harutyunyan, Vardan Bardakhchyan, Amalya Sargsyan, Mariam Mailyan, Mariam Sargsyan, Elen Baloyan, Nune Karapetyan, Marine Rushanyan, Gohar Mkrtchyan, Sahak Azizyan, Martin Harutyunyan, Gevorg Tamamyan
Mouthe Jimmy, Ndah Akelekeh, Metogo Junie, Akelekeh Aponglen Ndah, Bah Felix Juweh, Boah-Ju Bill Brisbane, Kemfang Ngowa