ecancermedicalscience

Case Report

Neuroendocrine carcinoma of the cervix presenting as intractable hyponatremic seizures due to paraneoplastic SIADH—a rare case report and brief review of the literature

31 Jul 2014
Santhosh Kuriakose, N Umadevi, Sheela Mathew, NK Supriya, KP Aravindan, DS Smitha, G Amritha Malini

Herein is presented an interesting case of small-cell neuroendocrine carcinoma of the cervix which initially manifests as seizures due to hyponatremia caused by paraneoplastic syndrome of inappropriate anti diuretic hormone (SIADH). Awareness of a paraneoplastic syndrome at presentation can lead to early diagnosis and early initiation of treatment. The management is also unique in that it combines treating the paraneoplastic aspects as well as targeting the tumour itself. Multimodality treatment gives the best outcome in this aggressive tumour.

Related Articles

Camilla Engelsmann, Gitte Wooler, Vladimira Horvat, Shailesh Balasaheb Kolekar
Simran Malik, Sudipta Mukherjee, Pralay Shankar Ghosh, Santanu Bagchi, Gaurav Goel, Soumyadip Chatterji, Saugata Sen, Debashree Guha Adhya, Sangeeta Das Bhattacharya, Sanjay Bhattacharya
Carmen Saiz, Angel Montero, Mercedes López, Bruno Zambrana, Beatriz Alvarez, Jeannette Valero, Raquel Ciervide, Ovidio Hernando, Mariola Garcia-Aranda, Emilio Sanchez, Leyre Alonso, Xin Chen-Zhao, Rosa Alonso, Carmen Rubio
Sasongko Hadi Priyono, Winardi Budiwinata, Budianto Tedjowitono, Effendy, Muhamad Daffa Ibnurasy Pratama
Rohini Sebastian, Josh Thomas Georgy, Arun George, Prisca Santhanam, Raiza Philip, Anjana Joel, Ajoy Oommen John, Deepa Susan Joy Philip, Divya Bala Thumaty, Thomas Alex Kodiatte, Ashish Singh, Rekha Pai