ecancermedicalscience

Case Report

Neuroendocrine carcinoma of the cervix presenting as intractable hyponatremic seizures due to paraneoplastic SIADH—a rare case report and brief review of the literature

31 Jul 2014
Santhosh Kuriakose, N Umadevi, Sheela Mathew, NK Supriya, KP Aravindan, DS Smitha, G Amritha Malini

Herein is presented an interesting case of small-cell neuroendocrine carcinoma of the cervix which initially manifests as seizures due to hyponatremia caused by paraneoplastic syndrome of inappropriate anti diuretic hormone (SIADH). Awareness of a paraneoplastic syndrome at presentation can lead to early diagnosis and early initiation of treatment. The management is also unique in that it combines treating the paraneoplastic aspects as well as targeting the tumour itself. Multimodality treatment gives the best outcome in this aggressive tumour.

Related Articles

Ya Haddy Sallah, Verna Vanderpuye, Rahel Ghebre, Khadija Warfa, Alex Mutombo Baleka, Hannah Naa Gogwe Ayettey Anie, Pa Omadou Sallah, Esayas Berhanu Enoro, Namugga Jane, Rose Anorlu
Callie Daniels-Howell, Rumalie Corvera, Lizzie Chambers, Alex Daniels, Rhea Jayma, B-Etta ‘Babes’ Ayon, Nenacia Nirena Ranali ‘Rana’ Mendoza, Fatima Lorenzo, Liza Naranjo, Carmen Auste, Poh Heng Chong, Mike Palfreman, Justin N Baker, Michael J McNeil, Megan Doherty, Julia Downing
Tushar Ambekar, Amey Oak, Sivaranjini Kannusamy, Sandhya Cheulkar, Riya R John, Shalmali Chavan, Saket Mendhe, Supriya Kadam, Mamta Lade, Ganesh Balasubramanium, Ashwin Desouza, Avanish Saklani, Rajesh Dikshit, Pankaj Chaturvedi, Sudeep Gupta
Joshua Agilinko, Sonam Patel, Jogitha Selvarajah, Nicholas Tekkis, Mathew Vithayathil, Suzette Samlalsingh
Deepak Sudhakaran, Anoushka Arora, Smriti Rana, Amirtha Thampi, Sunilkumar, Parth Sharma