ecancermedicalscience

Case Report

CD19 (➕) CD56 (–) myeloma arising in a patient who failed two courses of immunosupressive therapy for aplastic anaemia

14 Feb 2017
Nigel P Murray, M Amparo Ruiz, G Maximiliano Miranda

Patients diagnosed with severe aplastic anaemia and without a compatible bone marrow transplant donor are treated with immunosuppressive therapy. These patients are found with time to develop a clonal disease such as myelodysplasia or paroxysmal nocturnal haemoglobinuria. However, the development of plasma cell dyscrasias is rare. We report the case here of a patient treated with immunosuppressive therapy who went on to develop myeloma 11 months after being diagnosed with severe aplastic anaemia. We include here a review of the literature.

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