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AACR 2014 /
Effective use of ibrutinib in the treatment of ABC lymphoma tumours

5th - 9th Apr 2014

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Published: 01.05.14
Views: 1980

Dr Louis Staudt - National Cancer Institute, Bethesda, USA

At a press conference during AACR, Dr Staudt discussed the results of a Phase II trial of a new drug, ibrutinib, in diffuse large B-cell lymphoma.

The first trial was promising, with a 40 percent response in ABC sub-type tumours which saw a survival rate which increased from 3 months on average to 10 months on average with few side effects.

However, the drug had no impact on GCB sub-type tumours, hence tests must be done to check which patients will be appropriate for such treatment, an area where genomics is especially important.

Staudt notes the great benefit of ibrutinib as there are significantly less side effects than chemotherapy and it has eradicated tumours, in some cases for years.

Previous conferences: highlights



Founding partners

European Cancer Organisation European Institute of Oncology

Founding Charities

Foundazione Umberto Veronesi Fondazione IEO Swiss Bridge

Published by

Cancer Intelligence